Description: EMBL-EBI
europe (4392) institute (1127) bioinformatics (425)
[Section title] > Item 3
TreeFam is a database composed of phylogenetic trees inferred from animal genomes. It provides orthology/parology predictions as well the evolutionary history of genes. (see the BRCA2 gene family page as an example) . Search TreeFam (HMM-based protein sequence search vs. TreeFam & Pfam HMMs) Enter Protein Sequence here Insert into tree Insert into TreeFam gene tree using Parsimony ( super-fast, might insert into several branches) Maximum Likelihood ( more accurate, might take a bit longer)
Learn about how TreeFam builds families, alignments, and trees and how families defined in TreeFam.