Description: The Rosenmund lab studies basic principles of synaptic transmission with a major focus on the process of neurotransmitter release.
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In the Rosenmund Lab, we study the process of communication between neurons at their point of contact—the synapse. At the synapse, an incoming electrical response triggers the release of a chemical signal, the neurotransmitter, in a process called exocytosis. The neurotransmitter molecules activate an electrical response in the receiving cell and, thus, the signal is propagated. While many of the essential protein players in transmission at a chemical synapse have been defined, many open questions about the
Our overarching goal in the Rosenmund Lab is to understand how different proteins, structures or genes determine neurotransmitter release properties. Why does synaptic transmission differ between cell types? How do proteins work together to assure the speed and efficiency of synaptic exocytosis? We use diverse approaches to reveal the molecular mechanisms underlying synaptic processes
Principal Investigator Curriculum Vitae CC02 für Grundlagenmedizin Neurowiss. für zelluläre molek. Neurobiologie -AG Rosenmund- Charité Universitaetsmedizin Berlin Charitéplatz 1 10117 Berlin Germany Tel. +49-(0)30-450-639 061 christian.rosenmund(at)charite.de