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When taken by breastfeeding mothers, paroxetine is known to have adverse side effects on their infants. At two weeks postpartum, women taking selective serotonin reuptake inhibitors (SSRIs), including paroxetine, had 27% to 33% lower breastfeeding rates as compared to those who did not take antidepressants, with no significant differences in nursing rates between the different SSRI-exposed groups.

Paroxetine should be used with caution in breastfeeding women.

Any person who considers using Paxil for a child or teenager must weigh the potential risks with the clinical need. At the end of the study, 33% of the patients treated with paroxetine showed a reduction to zero or one panic attacks compared to 14% of the placebo recipients.

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