Centre for Policy on Ageing
It’s not enough to design new drugs.
For drugs to be effective, they have to be delivered safely and intact to affected areas of the body. And drug delivery, much like drug design, is an immensely complex task. Cutting-edge research and development like that conducted at the U.S. Department of Energy’s Oak Ridge National Laboratory can help solve some of the challenges associated with drug delivery.
In fact, ORNL researchers and collaborators at Wayne State University recently used a unique combination of experimentation and simulation to shed light on the design principles for improved delivery of RNA drugs, which are promising candidates in the treatment of a number of medical conditions including cancers and genetic disorders. Specifically, the research team discovered that the motions of a tRNA (or transfer RNA) model system can be enhanced when coupled with nanodiamonds, or diamond nanoparticles a
Centre for Policy on Ageing