numab.com - Numab Therapeutics AG

Description: numab, Drug Innovators, Swiss biotech company, development, antibody-based therapeutics, Swiss, biotech company, biotech, antibody, antibodies, antibody fragment, scFv, variable domain, Fv fragment, antibody discovery, antibody development, drug, drug discovery, drug development, high-affinity, high affinity, drug-like, highly stable, modular design, designed functionality, bi-specific, bispecific, tailored half-life, difficult target, ion channel, GPCR, native display

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Using a novel, rational process, our proprietary discovery and engineering technology yields multispecific antibody-based therapeutics with tailored pharmacokinetic properties that improve on first-generation antibody therapies in terms of potency, stability, effect duration, and safety. Alongside our own in-house pipeline programs we have a number of strong discovery and development partnerships with pharma and biotech.

We are establishing a proprietary pipeline of differentiated therapeutics by targeting clinically validated pathways with multispecific molecules to create novel mechanisms of action designed to differentiate from standard of care by superior efficacy and favorable safety. Our most advanced program, ND021, exemplifies this strategy by blocking immune-suppressive PD-(L)1 signaling with best-in-class potency and simultaneously triggering 4-1BB-mediated T cell stimulation specifically in the tumor microenviron

Numab Therapeutics AG Bachtobelstrasse 5 CH-8810 Horgen Switzerland Please contact us at [email protected] How to find us: By train & bus + Arriving at Zurich Airport, you reach us within less than an hour. Take the S2 train in direction to “Ziegelbrücke” and exit at “Horgen” or any train to Zurich Main Station, from where you choose either the S2 or S8 train to “Horgen”. In Horgen take Bus 121 until the “Risi/Dow” stop; our offices are a two minute walk from there.

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