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mRNA vaccines have taken the lead as the fastest vaccine candidates in accelerated treatment development for wide-spread epidemics. In this era of COVID-19, vaccine discovery is of utmost importance to win the fight against the pandemic that infected millions. However, there is a setback with these vaccines currently in clinical trials: the need for intense refrigeration or freezing for storage. With this barrier to distribution, the vaccines that obtain FDA approval will only reach a tiny fraction of the h
With NanoGen Predict, NanoGen aims to stabilize mRNA vaccines to take the next step in ensuring a vailable and affordable healthcare to all.
It is known that mRNA has a tendency to spontaneously degrade, and one cut can render the whole vaccine useless. To help unlock the key to the end of the special freeze storage needed to prevent mRNA degradation, NanoGen Predict uses Recurrent Neural Networks (RNNs) to analyze a mRNA sequence and give a prediction on the degradation rate at every nucleotide base pair. Trained on Eterna's RNA sequence dataset, NanoGen Predict provides the next step to the stabilization of the SARS-CO-V-2 vaccine for global d