Leish @ York | Leading the way on research on leishmaniasis in the UK
Description: A global pathology network supporting research on Leishmaniasis
Developing a human challenge model of Leishmania major infection as a tool for assessing vaccines against leishmaniasis. Developing a human challenge model of Leishmania major infection as a tool for assessing vaccines against leishmaniasis. Developing a human challenge model of Leishmania major infection as a tool for assessing vaccines against leishmaniasis. Developing a human challenge model of Leishmania major infection as a tool for assessing vaccines against leishmaniasis. Developing a human challenge
No vaccine against human leishmaniasis has yet been developed. What is needed is a rapid, cost effective means for early evaluation of the efficacy of candidate vaccines. Our solution to this roadblock is a is a Controlled Human Infection Model (CHIM) of sand fly initiated Leishmania major infection.
The primary outcome of this project is the development of an effective Leishmania major human challenge model with 100% lesion clearance after treatment. The secondary outcomes include the measurement of immune response parameters and analysis of lesion development.
Leish @ York | Leading the way on research on leishmaniasis in the UK