Our research is focused on elucidating the role of epigenetic mechanisms on the onset and progression of neurodegenerative diseases, particularly Parkinson’s and Alzheimer’s. We aimed at understanding how gene expression programs become altered in the brain contributing to neurodegeneration. Our translational neuroepigenetics program combines cutting edge multi-omic technologies with cellular physiology, molecular neuroscience and neuropathology to address mechanistic questions, to identify therapeutic targ
Research in our lab is aimed at elucidating the dynamic mechanisms of DNA methylation, which might contribute to onset and progression of the most prevalent neurodegenerative diseases of the elderly, Parkinson’s and Alzheimer’s.
Our research is focused on elucidating the role of epigenetic mechanisms in the onset and progression of neurodegenerative diseases, particularly Parkinson’s and Alzheimer’s. We seek to understand how gene expression profiles become altered in the brain and contribute to neurodegeneration. Our translational neuroepigenetics program combines cutting-edge, multi-omic technologies with cellular physiology, molecular neuroscience, and neuropathological assays to address mechanistic questions, identify therapeut