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Lisinopril, a medication used to treat high blood pressure, should be used with caution during pregnancy as it may harm the expected infant. It is important to adjust the dosage of Zestril (the brand name for Lisinopril) in individuals undergoing hemodialysis or those with reduced creatinine clearance.
There is no evidence of lisinopril causing cancer based on studies with mice. Even at high doses (135 milligrams per kg per day) administered for a long duration (92 weeks), no carcinogenicity was observed. This is equivalent to 84 times the maximum recommended daily human dose.
Lisinopril, sold under the brand name Prinivil, may cause slight declines in hemoglobin and hematocrit levels. These declines are usually not clinically significant unless there is another underlying cause of anemia in the patient.