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Plastics are widely used in our economy and each year, at least 350-400 million tons are being produced at a global level 1,2 . Due to poor recycling and low circular use, tens of millions of tons accumulate annually in marine and terrestrial environments. While it has become obvious that micro and macroplastics contaminate our environments recent research has identified few bacteria and fungi actively degrading plastics by enzymatic reactions. In general these are promiscuous enzymes (hydrolases) acting on

Cite: Buchholz, P.C.F., Feuerriegel, G., Zhang, H., Perez-Garcia, P., Nover, L.-L., Chow, J., Streit, W.R. and Pleiss, J (2022); Plastics degradation by hydrolytic enzymes: The Plastics-Active Enzymes Database - PAZy (download link for reference manager)

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