neuroamer.com - Neuroamer | An MD-PhD student's blog about Neuroscience, Neurology, and Psychiatry

Description: An MD-PhD student's blog about Neuroscience, Neurology, and Psychiatry

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Semaglutide (Ozempic/Wegovy)  is part of a class of drugs that mimic the action of the peptide GLP-1, a hormone that’s secreted from the small intestine in response to food.

GLP-1 and drugs that mimic it’s actions like the ‘glutides’ have many actions throughout the body, but the most important direct effects are thought to be on the brain, pancreas and stomach.

The ‘glutides’ were originally developed as treatments for Type II diabetes. By decreasing appetite and slowing digestion they attenuate the amount of glucose entering the bloodstream. And by increasing insulin secretion and decreasing glucagon, they help get excess glucose out of the bloodstream.

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