mutationalsignatures.com - Mutagenesis in Medicine | University of Cambridge

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Oncology research has always been a passion of mine. Throughout my undergraduate study at The Pennsylvania State University, I made a point of exploring the full spectrum of biomedical research, from basic gene regulation work to clinical studies of chemotherapeutic toxicity.

At the University of Cambridge, I earned an MPhil in Epidemiology. I then continued on to a PhD in Data Science as an NIH Oxford-Cambridge Scholar and a Gates Cambridge Scholar. Under the under the supervision of both Dr. Serena Nik-Zainal and Professor Paul Pharoah, my research focuses on the association between germline risk-conferring variants and somatic mutational signatures in breast cancer.

Alexander is an honorary specialty registrar in Clinical Genetics and a post-doctoral researcher funded by the NIHR. During his PhD Alexander explored the development of the human liver and intestine at single-cell resolution and developed the first stem cell based liver organoid model, which offers great promise as a tool to study the liver in health and disease.