Description: The Chodera lab at the Memorial Sloan-Kettering Cancer Center
The Chodera lab at the Memorial Sloan-Kettering Cancer Center
Changing drug discovery one ratio of partition functions at a time
The Chodera lab uses computation and experiment to develop quantitative, multiscale models of the effects of small molecules on biomolecular macromolecules and cellular pathways and understand the functional and therapeutic ramifications of mutations. The group utilizes physical models, rigorous statistical mechanics, and open source software development practices with overall goals of engineering novel therapeutics and tools for chemical biology, predicting resistance or susceptibility to therapy, and unde