Description: Update 10/7/23 - Katalin Kariko and Drew Weissman have been awarded the 2023 Nobel Prize in Physiology or Medicine for their 2005 paper that is the basis for the mRNA exercise (see sample screenshot below). The announcement highlighted Fig 3D of that paper (simulated in Part 3, step 12 of the mRNA exercise). Updates 8/16/23- Case It v705
Update 1/11/23 : Case It Mobile is currently being expanded to include more cases with links to videos of simulation results. This will enable students to analyze cases on smartphones and other mobile devices, without having to download and run Case It v705 . Click here for examples of the new format for Case It Mobile . Update 12/31/22 : A version of Case It v705 suitable for use with Ventura (MacOS 13) is now available on the download page. Read this important information before using the Ventura version
Case It v705 performs common laboratory procedures on any DNA or protein sequence and can be downloaded free of charge for educational use. Sequences included with the download enable students to analyze a variety of cases with a focus on genetic and infectious diseases. The CRISPR exercise enables students to learn basic molecular biology techniques while recreating and analyzing Nobel Prize -winning research experiments . The first study to successfully use CRISPR to treat a genetic condition is analyzed
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