Systems Biology for Energy and the Environment | Genomic Science Program
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Cultivation and genetic analysis have been the primary means used to study gene function and the behavior of microbes. However, these classical approaches require isolating and culturing microorganisms in the lab. This severely limits scientists’ knowledge of microbes that cannot yet be cultivated in the lab. Moreover, the interactions that occur between microbes when they grow together in a community cannot be studied in isolated organisms. To address these challenges, this research developed two technolog
Scientists have several approaches to predict functional properties of a given protein that use the protein’s amino acid sequence to build a computational model. Scientists create such models employing both classical statistical methods and modern-day machine learning computational approaches. One of those statistical methods, called regression analysis, associates a given amino acid sequence with an experimentally measured functional property of a protein. To increase the amount of data available to make f
Systems Biology for Energy and the Environment | Genomic Science Program