Description: ACIR's mission is to fast-track cancer immunotherapy research by helping researchers stay on top of the new literature in this fast-moving and multifaceted field. Free of charge.
Featured A few CD4+ T cells go a long way against immune-evasive tumors Investigating the contributions of CD4+ T cells to antitumor immunity, Kruse, Buzzai, Shridhar, and Braun et al. unraveled a mechanism through which a small number of CD4+ T cells can eradicate MHC-deficient, IFNγ-unresponsive tumors that...
The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies